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Well-differentiated liposarcoma
3 associated genes
4 signs/symptoms
PROTEIN INTERACTIONS: 1
Prune belly syndrome
1 OMIM reference -
1 associated gene
34 signs/symptoms
Well-differentiated liposarcoma
Prune belly syndrome

CDK4
(UniProt - OMIM)
 CHRM3
(UniProt - OMIM)
HMGA2
(UniProt - OMIM)
MDM2
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
MDM2
(0.49)
CHRM3


Citations in the biomedical literature:


Well-differentiated liposarcoma
CDK4 HMGA2 MDM2
Prune belly syndrome
CHRM3



Well-differentiated liposarcoma
Prune belly syndrome

Synonym(s):
- ALT
- Atypical lipoma
- Atypical lipomatous tumor
- WDLS
Synonym(s):
- Eagle-Barret syndrome
- Urethral obstruction sequence
Classification (Orphanet):
- Rare oncologic disease
Classification (Orphanet):
(no data available)
Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -
Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: adult
Type of inheritance: sporadic
Epidemiological data:
(no data available)
External references:
No OMIM references
No MeSH references
External references:
1 OMIM reference -
2 MeSH references: C536477 / D011535
Well-differentiated liposarcoma
Prune belly syndrome

Very frequent
- Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma
- Subcutaneous nodules / lipomas / tumefaction / swelling

Occasional
- Functional anomalies of the kidney and the urinary tract
- Intestinal transit disorder


Very frequent
- Absent / hypotonic / flaccid abdominal wall muscles
- Bladder and ureter anomalies
- Hypoplastic lungs / pulmonary hypoplasia / agenesis
- Megaureter / hydronephrosis / pyeloureteral junction syndrome
- Sterility / hypofertility
- Undescended / ectopic testes / cryptorchidia / unfixed testes
- Urethral anomalies / stenosis / posterior urethral valves / megalocystis
- Vesicorenal / vesicoureteral reflux

Frequent
- Constipation
- Multicystic kidney / renal dysplasia
- Oligoamnios
- Recurrent urinary infections
- Renal failure
- Repeat respiratory infections
- Rib structure anomalies
- Small / atrophic / hypoplastic testes / monorchism / microorchidism / anorchia

Occasional
- Atrial septal defect / interauricular communication
- Colonic / intestinal volvulus
- Failure to thrive / difficulties for feeding in infancy / growth delay
- Hip dislocation / dysplasia / coxa valga / coxa vara / coxa plana
- Imperforate anus / rectum atresia / agenesis / recto-vaginal / vesical / perineal fistula
- Intellectual deficit / mental / psychomotor retardation / learning disability
- Intestinal atresia / stenosis / absence / agenesis / hypoplasia (excludes duodenum)
- Intestinal / gut / bowel malrotation
- Patent ductus arteriosus
- Pectus excavatum
- Scoliosis
- Stillbirth / neonatal death
- Talipes-varus / metatarsal varus
- Tetralogy of Fallot / trilogy of Fallot
- Urogenital sinus
- Uterine / uterus / Fallopian tubes anomalies
- Ventricular septal defect / interventricular communication
- Vertebral segmentation anomaly / hemivertebrae